Fill in the Blanks
Key drug actions and indications.
Class
:
Mechanism
of
action
:
time
through
the
;
can
interrupt
re
-
entrant
pathways
;
;
acts
directly
on
sinus
pacemaker
cells
.
It
is
the
drug
of
choice
for
PSVT
.
Indications
:
Conversion
of
PSVT
to
sinus
rhythm
.
May
convert
PSVT
due
to
Wolff
-
ParkinsonWhite
syndrome
.
Not
effective
atrial
fibrillation
/
flutter
.
Contraindications
:
Second
or
third
-
degree
"
block
or
Sick
Sinus
Syndrome
Atrial
flutter
/
atrial
fibrillation
Ventricular
Tachycardia
Hypersensitivity
to
adenosine
Adverse
Reactions
:
,
shortness
of
breath
,
chest
pain
,
headache
,
paresthesia
,
diaphoresis
,
palpitations
,
,
nausea
,
.
Drug
Interactions
:
Methylxanthines
(
theophylline
-
like
drugs
)
antagonize
the
effects
of
adenosine
.
Dipyridamole
(
Persantine
)
potentiates
the
effects
of
adenosine
Carbamazepine
(
Tegretol
)
and
may
potentate
the
AV
Node
blocking
effects
of
adenosine
.
Dosage
and
Administration
Adult
:
mg
over
1
-
3
seconds
;
If
no
response
after
1
-
2
minutes
,
administer
mg
over
1
-
3
seconds
,
Maximum
total
dose
=
mgs
.
Pediatric
:
0
.
mg
/
kg
rapid
IV
;
If
no
response
after
1
-
2
minutes
,
administer
0
.
/
kg
over
1
-
3
seconds
,
Maximum
total
dose
=
mgs
.
Maximum
single
dose
=
mgs
.
Duration
of
action
Onset
and
peak
effects
in
seconds
;
duration
seconds
.
Special
Considerations
Short
half
-
life
limits
side
effects
in
most
patients
.
Class
:
,
anesthesia
induction
agent
Mechanism
of
Action
:
that
acts
at
the
level
of
the
reticular
activating
system
.
Indications
:
Premedication
for
RSI
Contraindications
:
,
labor
/
delivery
,
or
.
Adverse
Reactions
:
Apnea
of
short
duration
,
,
hypoventilation
,
hypotension
,
,
nausea
,
vomiting
,
involuntary
muscle
movement
.
Drug
Interactions
:
Effects
may
be
enhanced
when
given
with
other
CNS
depressants
.
Dosage
and
Administration
:
Adult
:
.
?
0
.
mg
/
kg
IV
(
typical
adult
dose
is
)
Pediatric
:
.
-
.
/
kg
IV
/
IO
to
assist
with
RSI
(
over
10
years
old
)
,
one
time
only
,
max
.
Duration
of
action
:
Onset
:
less
than
minute
Peak
Effect
:
minute
Duration
:
-
minutes
Special
Considerations
:
Safety
:
Use
caution
weighing
fetal
risk
and
maternal
benefit
in
pregnant
Class
:
.
Mechanism
of
Action
Inhibits
and
promotes
excretion
of
,
,
.
Indications
CHF
;
Contraindications
Hypovolemia
,
anuria
,
(
relative
contraindication
)
;
,
hepatic
coma
.
Adverse
Reactions
May
exacerbate
Hypovolemia
,
,
ECG
changes
,
,
hypochloremia
,
hyponatremia
Drug
Interactions
Lithium
toxicity
may
be
potentiated
by
depletion
.
Digitalis
toxicity
may
be
potentiated
by
depletion
.
Dosage
and
Administration
Adult
:
.
-
.
mg
/
kg
injected
slowly
IV
.
(
Medical
Control
Option
)
Pediatric
:
mg
/
kg
/
dose
IV
,
IO
.
(
Medical
Control
Option
)
Duration
of
Action
Onset
:
minutes
.
Peak
Effects
:
-
minutes
.
Duration
:
-
hours
.
Special
Considerations
safety
:
Ototoxicity
and
deafness
can
occu
r
Class
:
,
anesthetic
Mechanism
of
Action
:
receptors
and
minimizes
activity
,
affecting
the
association
pathways
of
the
brain
between
the
thalamus
and
the
limbic
system
.
Indications
:
delirium
,
management
,
procedural
sedation
Contraindications
:
,
conditions
where
hypertension
could
be
dangerous
to
the
patient's
care
.
Adverse
Reactions
:
,
dysrhythmia
,
bronchodilation
,
.
Drug
Interactions
:
Ketamine
the
effects
of
opiates
,
barbiturates
,
and
nondepolarizing
neuromuscular
blockers
.
Dosage
and
Administration
:
Adult
:
Excited
Delirium
/
kg
IM
only
Pain
:
.
-
.
mg
/
kg
IV
,
may
repeat
IV
dose
once
in
10
minutes
Or
mg
/
kg
IM
/
IN
,
may
repeat
IM
/
IN
dose
once
in
20
minutes
.
RSI
:
/
kg
IV
Analgesia
and
sedation
for
intubated
patient
:
-
/
kg
IV
every
30
-
45min
(
Not
allowed
in
all
systems
?
know
your
local
protocols
)
:
Not
recommended
Duration
of
action
:
Onset
:
minutes
Peak
Effect
:
-
-
hours
Duration
:
-
hours
Special
Considerations
:
Safety
:
Contraindicated
for
use
during
pregnancy
.
Use
in
caution
in
patients
due
to
a
higher
risk
of
renal
and
fatal
GI
adverse
reactions
.
|
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