Unit 3 Hematology

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A short practice exam

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Chloe Bellamy

United States

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Unit 3 Hematology


Froggy Jumps Unit 3 HematologyOnline version A short practice exam by Chloe Bellamy 1 Hereditary spherocytosis is most commonly caused by a defect in which protein? a Spectrin b G6PD c Hemoglobin A 2 Which inheritance pattern is most common in hereditary spherocytosis? a Autosomal recessive only b Autosomal dominant c X‑linked recessive 3 What classic triad is associated with hereditary spherocytosis? a Jaundice, anemia, splenomegaly b Bone pain, fever, jaundice c Hematuria, anemia, edema 4 Which RBC index is commonly elevated in hereditary spherocytosis? a MCHC b RDW c MCV 5 Hereditary elliptocytosis is most often caused by defects in which structure? a Hemoglobin b Iron transport c Spectrin self‑association 6 Southeast Asian ovalocytosis provides protection against which disease? a Malaria b Tuberculosis c Hepatitis 7 G6PD deficiency is inherited in which pattern? a Autosomal dominant b X‑linked c Autosomal recessive 8 What forms inside RBCs during oxidative stress in G6PD deficiency? a Heinz bodies b Basophilic stippling c Howell‑Jolly bodies 9 Which food is a classic trigger for hemolysis in G6PD deficiency? a Fava beans b Wheat c Almonds 10 Sickle cell disease results from a mutation in which globin chain? a Gamma b Alpha c Beta 11 What is the earliest renal complication in sickle cell disease? a Hyposthenuria b Kidney stones c Renal failure 12 Individuals with sickle cell trait typically produce HbA and HbS in what ratio? a 90:10 b 60:40 c 40:60 13 Which hemoglobin is elevated in beta‑thalassemia major? a HbA2 and HbF b HbA c HbE 14 Infants with beta‑thalassemia major typically present at what age? a At birth b Age 3–5 c First year of life 15 Hemoglobin Bart’s (γ4) is associated with which condition? a Alpha‑thalassemia major b Beta‑thalassemia minor c Sickle cell trait 16 Aplastic anemia is characterized by which CBC finding? a Pancytopenia b Leukocytosis c Thrombocytosis 17 Which virus is associated with aplastic anemia? a Rhinovirus b Epstein‑Barr virus c Influenza 18 PNH is caused by a mutation in which gene? a G6PD b PIGA c SPTA1 19 Which proteins are decreased on flow cytometry in PNH? a CD3 and CD4 b CD55 and CD59 c CD14 and CD16 20 Hypothyroidism typically causes what type of anemia? a Microcytic b Sideroblastic c Normocytic to macrocytic

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Unit 3 Hematology

Froggy Jumps

About this activity

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Unit 3 HematologyOnline version

by Chloe Bellamy

Hereditary spherocytosis is most commonly caused by a defect in which protein?

Which inheritance pattern is most common in hereditary spherocytosis?

What classic triad is associated with hereditary spherocytosis?

Which RBC index is commonly elevated in hereditary spherocytosis?

Hereditary elliptocytosis is most often caused by defects in which structure?

Southeast Asian ovalocytosis provides protection against which disease?

G6PD deficiency is inherited in which pattern?

What forms inside RBCs during oxidative stress in G6PD deficiency?

Which food is a classic trigger for hemolysis in G6PD deficiency?

Sickle cell disease results from a mutation in which globin chain?

What is the earliest renal complication in sickle cell disease?

Individuals with sickle cell trait typically produce HbA and HbS in what ratio?

Which hemoglobin is elevated in beta‑thalassemia major?

Infants with beta‑thalassemia major typically present at what age?

Hemoglobin Bart’s (γ4) is associated with which condition?

Aplastic anemia is characterized by which CBC finding?

Which virus is associated with aplastic anemia?

PNH is caused by a mutation in which gene?

Which proteins are decreased on flow cytometry in PNH?

Hypothyroidism typically causes what type of anemia?