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La localización, el origen y el impacto de las plaquetas en el microambiente tumoral dependen del tipo de tumor

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La localización, el origen y el impacto de las plaquetas en el microambiente tumoral dependen del tipo de tumor

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Descubre si estas ideas sobre plaquetas y metástasis son ciertas

Created by

Estefania Laguna Flores
Estefania Laguna Flores
Mexico

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La localización, el origen y el impacto de las plaquetas en el microambiente tumoral dependen del tipo de tumor
 

La localización, el origen y el impacto de las plaquetas en el microambiente tumoral dependen del tipo de tumorOnline version

Descubre si estas ideas sobre plaquetas y metástasis son ciertas

by Estefania Laguna Flores
1

Existen mecanismos por los que las plaquetas favorecen la metástasis, como la EMT y la protección de CTCs.

2

La localización de las plaquetas en tumores sólidos está bien caracterizada.

3

Debido al diseño experimental, las plaquetas pueden o no tener un efecto en el crecimiento del tumor primario.

4

En los B16F1, mayor granzima B se asocia con menor peso tumoral.

5

PD-L1 es más bajo en AT3 que en B16F1.

6

Las plaquetas adheridas a vasos tumorales se observaban solo como agregados multicelulares, nunca individualmente.

7

Los tumores AT-3 en ratones trombocitopénicos muestran una tendencia a una menor proliferación de células tumorales.

8

En ratones con tumores B16F1 trombocitopénicos, aumento la expresión de 24 citocinas.

 
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