Iron Uptake & IDA (Robbins)

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Robbins Pathology focus

Created by

Priya Darshini

India

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Froggy Jumps Iron Uptake & IDA (Robbins)Online version Robbins Pathology focus by Priya Darshini 1 Which protein exports iron from enterocytes into the bloodstream? a DMT1 b Ferritin c Ferroportin 2 What enzyme reduces Fe3+ to Fe2+ for uptake at the apical surface of enterocytes? a Apolipoprotein E b Hephaestin c Ferrireductase (DCYTB) 3 Which hormone decreases intestinal iron absorption by inhibiting ferroportin? a Hepcidin b Erythropoietin c Transferrin 4 In iron deficiency, what happens to ferroportin activity in enterocytes? a Increases to raise iron absorption b Decreases due to ferritin accumulation c Becomes inactive 5 Which molecule stores iron intracellularly in enterocytes and other cells? a Transferrin b Ferritin c Hepcidin 6 Which condition characterizes Robbins-described iron absorption regulation? a Low hepcidin in iron deficiency b High ferritin causing iron overload c High hepcidin in iron deficiency 7 Which lab finding is typical of iron deficiency anemia? a Normal ferritin with high iron b Low ferritin c High ferritin 8 Which factor worsens iron absorption efficiency in the duodenum? a Low gastric acidity b Excess hepcidin c High iron stores 9 What is the primary site of dietary iron absorption in the body as per Robbins? a Ileum b Duodenum (proximal small intestine) c Stomach 10 Which sequence correctly describes iron uptake from lumen to blood? a Ferritin reduction, ferroportin transport, transferrin uptake b DMT1 export, ferritin storage, hepcidin release c Fe3+ to Fe2+ reduction, DMT1 transport, ferroportin export

Froggy Jumps

Iron Uptake & IDA (Robbins)Online version

Robbins Pathology focus

by Priya Darshini

Which protein exports iron from enterocytes into the bloodstream?

DMT1

Ferritin

Ferroportin

What enzyme reduces Fe3+ to Fe2+ for uptake at the apical surface of enterocytes?

Apolipoprotein E

Hephaestin

Ferrireductase (DCYTB)

Which hormone decreases intestinal iron absorption by inhibiting ferroportin?

Hepcidin

Erythropoietin

Transferrin

In iron deficiency, what happens to ferroportin activity in enterocytes?

Increases to raise iron absorption

Decreases due to ferritin accumulation

Becomes inactive

Which molecule stores iron intracellularly in enterocytes and other cells?

Transferrin

Ferritin

Hepcidin

Which condition characterizes Robbins-described iron absorption regulation?

Low hepcidin in iron deficiency

High ferritin causing iron overload

High hepcidin in iron deficiency

Which lab finding is typical of iron deficiency anemia?

Normal ferritin with high iron

Low ferritin

High ferritin

Which factor worsens iron absorption efficiency in the duodenum?

Low gastric acidity

Excess hepcidin

High iron stores

What is the primary site of dietary iron absorption in the body as per Robbins?

Ileum

Duodenum (proximal small intestine)

Stomach

Which sequence correctly describes iron uptake from lumen to blood?

Ferritin reduction, ferroportin transport, transferrin uptake

DMT1 export, ferritin storage, hepcidin release

Fe3+ to Fe2+ reduction, DMT1 transport, ferroportin export

You can integrate the game into an LMS compatible with LTI 1.1 or LTI 1.3 such as Canvas, Moodle, or Blackboard. This way, the scores will be automatically saved into the platform’s gradebook.

Iron Uptake & IDA (Robbins)

Froggy Jumps

About this activity

Created by

Download the paper version to play

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Iron Uptake & IDA (Robbins)Online version

by Priya Darshini

Which protein exports iron from enterocytes into the bloodstream?

What enzyme reduces Fe3+ to Fe2+ for uptake at the apical surface of enterocytes?

Which hormone decreases intestinal iron absorption by inhibiting ferroportin?

In iron deficiency, what happens to ferroportin activity in enterocytes?

Which molecule stores iron intracellularly in enterocytes and other cells?

Which condition characterizes Robbins-described iron absorption regulation?

Which lab finding is typical of iron deficiency anemia?

Which factor worsens iron absorption efficiency in the duodenum?

What is the primary site of dietary iron absorption in the body as per Robbins?

Which sequence correctly describes iron uptake from lumen to blood?

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