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Estrecho margen terapéutico

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Estrecho margen terapéutico

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Rango terapéutico estrecho

Created by

Liliana Roldan Torres
Liliana Roldan Torres
Colombia

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Estrecho margen terapéutico
 

Estrecho margen terapéuticoOnline version

Rango terapéutico estrecho

by Liliana Roldan Torres
1

Un incremento del 50% de la dosis siempre está dentro del rango terapéutico.

2

Digoxina y litio son ejemplos clásicos de fármacos con margen terapéutico estrecho.

3

La variabilidad entre pacientes puede afectar la concentración terapéutica de estos fármacos.

4

La monitorización de fármacos se utiliza solo en investigación, no en clínica real.

5

Un fármaco de margen estrecho no requiere ajuste en pacientes con insuficiencia renal.

6

Los fármacos de margen estrecho tienen un rango de seguridad muy amplio.

7

Un fármaco con margen terapéutico estrecho necesita monitorización plasmática frecuente.

8

Pequeñas variaciones de dosis pueden provocar toxicidad en fármacos de margen estrecho.

9

Todo fármaco con ventana terapéutica estrecha es inevitablemente tóxico.

10

El objetivo es mantener la concentración en un rango definido para evitar efectos adversos.

 
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