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Suffixes - Headings: Canine Parvovirus Infection [MVZ]

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Suffixes - Headings: Canine Parvovirus Infection [MVZ]

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Created by

Nahum López Gómez
Nahum López Gómez
Mexico

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Suffixes - Headings: Canine Parvovirus Infection [MVZ]
 

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Suffixes - Headings: Canine Parvovirus Infection [MVZ]Online version

Choose the right heading for each paragraph

by Nahum López Gómez
1


Parvoviral enteritis is a highly contagious viral disease that commonly affects young , unvaccinated dogs . Clinical signs include anorexia , lethargy , vomiting , and diarrhea , which is often hemorrhagic . Diagnosis is typically based on history , physical examination findings , and fecal antigen testing .


The etiological agent of parvoviral enteritis in dogs is canine parvovirus ( CPV ) . CPV is a nonenveloped , single - stranded DNA virus . Although its exact origin is unknown , CPV is believed to have arisen from feline panleukopenia virus .


Replication of canine parvovirus occurs initially in the lymphoid tissue of the oropharynx , with systemic illness resulting from subsequent hematogenous dissemination .


CPV preferentially infects and destroys rapidly dividing cells of the small intestinal crypt epithelium , lymphopoietic tissue , and bone marrow . Destruction of the intestinal crypt epithelium results in epithelial necrosis , villous atrophy , impaired absorptive capacity , and disrupted gut barrier function , with the potential for bacterial translocation and bacteremia .


Lymphopenia and neutropenia develop secondary to destruction of hematopoietic progenitor cells in the bone marrow and lymphopoietic tissues and are further exacerbated by an increased systemic demand for leukocytes .


Infection in utero , or in pups less than 8 weeks old or born to unvaccinated dams without naturally occurring antibodies , can result in myocardial infection , necrosis , and myocarditis . Myocarditis , presenting as acute cardiopulmonary failure or delayed , progressive cardiac failure , can occur with or without clinical signs of enteritis .


Infected dogs shed virus in feces within 4 ? 5 days following exposure , often before clinical signs develop , throughout the period of illness , and for approximately 10 days after clinical recovery .


G Overview of Parvoviral Enteritis
D Cause and Virus Characteristics
A Initial Viral Replication and Spread
C Target Cells and Tissue Damage
F Effects on Blood Cells and Immune System
B Myocardial Infection in Young or Unprotected Puppies
E Viral Shedding and Transmissio n

 
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