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Bacterial structure and organisation

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Bacterial structure and organisation

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Created by

Jessica
Jessica
United Kingdom

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Bacterial structure and organisation
 

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Bacterial structure and organisationOnline version

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by Jessica
1

The bacterial chromosome is typically a , circular molecule of - stranded DNA . It has one origin of and many genes with short repetitive sequences . The chromosome is compacted into a dense , irregularly shaped structure called the , which is membrane - bound ( e . g . , not in a ) .

2

The chromosome is large , often several base pairs , and must be highly compacted to fit within the . The bacterial chromosome is organised into 50 ? 100 loop domains , stabilised by - ( NAPs ) . Loop domains allow regulation of expression and help organise the chromosome efficiently within the small cellular space .

3

DNA gyrase ( topoisomerase ) introduces supercoils , essential for compacting the chromosome . Negative facilitates strand separation and makes DNA more accessible for polymerase and replication machinery .

Topoisomerase relaxes supercoils when supercoiling could or stop cellular processes . This compaction and supercoiling help with and replication .

 
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