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Crossword Puzzle
Crossword Puzzle

Repaso Inmunosupresores

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Repaso Inmunosupresores

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About this activity

Actividad final para repasar conceptos claves de los inmunosupresores mas comunes

Created by

Florencia
Florencia
Argentina

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Repaso Inmunosupresores
 

Crossword Puzzle

Repaso InmunosupresoresOnline version

Actividad final para repasar conceptos claves de los inmunosupresores mas comunes

by Florencia
1

Inhibidor de calcineurina que se une a ciclofilina; causa hirsutismo e hiperplasia gingival.

2

Macrólido que inhibe calcineurina uniéndose a FKBP-12; es más diabetogénico que la ciclosporina.

3

Inhibidor de mTOR; no es nefrotóxico pero produce hiperlipidemia y trombocitopenia.

4

Antagonista del ácido fólico que inhibe la enzima dihidrofolato reductasa (DHFR).

5

Molécula usada en nuestro país como rescate en altas dosis de metotrexato.

6

Fosfatasa inhibida por ciclosporina y tacrolimus; esencial para la activación del NFAT.

7

Proteína inhibida por sirolimus; regula el ciclo celular y la proliferación linfocitaria.

8

Enzima que degrada metotrexato extracelular en casos de toxicidad severa o insuficiencia renal.

9

Concentración del fármaco justo antes de la siguiente dosis; es el momento estándar para el monitoreo.

10

Efecto adverso común de ciclosporina y tacrolimus; principal limitante de su uso crónico. También puede producirlo el metotrexato.

11

Sigla del monitoreo terapéutico de fármacos; herramienta para personalizar la dosis.

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