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Muscle Contraction Sequence

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Muscle Contraction Sequence

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Muscle Contraction Sequence
 

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Muscle Contraction SequenceOnline version

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by Danielle T
1

1 . A motor neuron fires an action potential down its . is released from the axon terminal , crosses the synaptic cleft and binds to receptors on the sarcolemma of the muscle . Influx of and efflux of produces a special type of graded potential called an plate potential ( EPP ) in the muscle .
2 . The EPP will lead to an action potential in the muscle that travels along the and into the tubules . The action potential opens voltage gated channels in the reticulum causing the release of calcium into the cytosol .
3 . The calcium binds to , causing to move and expose myosin - binding sites on . Myosin heads hydrolyze to ADP and Pi , forming - bridges with actin . The stroke pulls the actin filaments toward the center of the sarcomere the muscle ( contraction ) . Another ATP binds to myosin , breaking the cross - bridge , and the cycle repeats if calcium remains elevated . When the signal ends ( no more acetylcholine in the synaptic cleft so no more AP ) , calcium is actively pumped back into the , tropomyosin once again covers the myosin binding sites leading to relaxation of the muscle .

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