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Completa , regulación enzimatica , inhibidores y enzimas sericas , grupo 3

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Completa , regulación enzimatica , inhibidores y enzimas sericas , grupo 3

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Grupo 3

Created by

Larianny
Larianny
Dominican Republic

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Completa , regulación enzimatica , inhibidores y enzimas sericas , grupo 3
 

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Completa , regulación enzimatica , inhibidores y enzimas sericas , grupo 3Online version

Grupo 3

by Larianny
1

Los inhibidores compiten directamente con el sustrato por el sitio activo de la enzima , lo que aumenta el valor de la Km por no altera la Vmax .

2

La regulación ocurre cuando una molécula efectora se une a un sitio distinto al sitio activo , provocando un cambio conformacional que altera la actividad de la enzima .

3

La elevación de la enzima sérica es un marcador clínico clásico utilizado para el diagnóstico de infarto agudo de miocardio o daño en el músculo esquelético .

4

La es un precursor inactivo de una enzima que requiere de una hidrolisis parcial o cambio químico para convertirse en su forma activa , como sucede con el pepsinógeno .

5

En la inhibición el inhibido se une al complejo enzima - sustrato y no a la enzima libre , disminuyendo tanto Vmax como Km .

6

La unión de un modulador alostérico provoca un aumento en la afinidad de la enzima por su sustrat o

7

La presencia de enzimas intracelulares en el sanguíneo suele ser un indicador clínico de daño celular o tisula r

8

Un inhibidor se une a la enzima mediante enlaces covalentes fuertes , desactivándola de forma permanente

9

Los efectores alostericos modifican la actividad enzimatica al inducir un cambio en la estructura de la proteína

10

En el mecanismo de retroalimentación , el producto final de una vía inhibe a la primera enzima de la misma

 
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