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Crossword Puzzle
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Oncogenes and Tumour suppressor and inheritance of cancer

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Oncogenes and Tumour suppressor and inheritance of cancer

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About this activity

PBL 5.05

Created by

Lorrianne Joseph
Lorrianne Joseph
United Kingdom

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Oncogenes and Tumour suppressor and inheritance of cancer
 

Crossword Puzzle

Oncogenes and Tumour suppressor and inheritance of cancerOnline version

PBL 5.05

by Lorrianne Joseph
1

Genes that possess normal gene products and stimulate normal call development and can lead to the formation of growth factors

2

the type of mutation that oncogenes fall under

3

A gene thats normal function is to constrain cell proliferation and partial or complete inactivation leads to an increased likelihood of cancer development.

4

What is the type of mutation does mutations of tumour suppressor genes fall under

5

An example of a tumour suppressor gene that can arrest the cell cycle.

6

The type of deficiency in proteins that leads to defective repair of mutations.

7

The pathway which starts with the suppressor of the APC gene and with the oncogene mutation of K-Ras

8

an autosomal dominant syndrome caused by germline mutation in the APC gene.

9

An autosomal dominant syndrome caused by a germline mutation in one of the DNA mismatch repair genes.

10

The name of the complex where the APC inhibits the activation of the beta-catenin.

11

the percentage of the lifetime risk of patients with FAP developing colon cancer in their lifetime.

12

The proto-oncogene that mutates during adenomas stage in the adenoma-carcinoma pathway.

13

The gene that arises from mutant proto-oncogenes.

14

The reason why you would be offered earlier colonoscopies through clinics via the GP.

15

Mutations in mismatch repair deficiency tend to accumulate in (BLANK), forming microsatellite repeats.

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