Matching Pairs Pharm 231 neuropsych, OB, V/M, blood and blood productsOnline version matching drug, indications, class, adverse reactions and interactions by Amanda 1 Sertraline (SSRI), & Duloxetine (SNRI): Depression, anxiety, and neuropathic pain 2 Bupropion: Depression and smoking cessation 3 Amitriptyline: Depression, anxiety, and neuropathic pain 4 Diazepam: Severe anxiety, alcohol withdrawal, seizure disorders, and insomnia 5 Benztropine: Parkinson’s symptoms (tremors, rigidity, drooling) 6 Haloperidol & Quetiapine: Schizophrenia, acute psychosis, and manic episodes of bipolar disorder 7 Phenytoin, Ethosuximide, Divalproex, & Carbamazepine: 8 Phenytoin: seizures 9 Ethosuximide and Divalproex: seizures 10 Phenobarbital: Anxiety, insomnia, and seizure disorders 11 Lithium: Acute manic episodes and maintenance of bipolar disorder 12 Methylphenidate (Ritalin): ADHD 13 Carbidopa-Levodopa: Parkinson’s disease 14 Phenelzine (MAOI): Resistant depression (Dopaminergic): Anxiety, nervousness, and cardiovascular effects (Antipsychotics): Extrapyramidal symptoms (EPS), Neuroleptic Malignant Syndrome (NMS), weight gain, and QT prolongation (NDRI): CNS hyperactivity, weight loss, and suicidality (CNS Stimulant): Sudden cardiac death in children with cardiac defects (TCA): Sedation, suicidality, and anticholinergic effects Various types of seizure disorders (focal, generalized, status epilepticus, or absence) (Antiepileptics): Bone marrow suppression, liver damage, and severe rashes (MAOI): Hypertensive emergency (Hydantoin): CNS suppression, gingival hyperplasia, and liver damage (Barbiturate): Severe CNS and respiratory depression Sertraline and Duloxetine (SSRI/SNRI): Serotonin syndrome, loss of libido, and suicidality (Anticholinergic): Dry mouth, constipation, and blurred vision (Antimanic): Slurred speech/tremors (<1.5 mEq/L) progressing to seizures and death (>2.5 mEq/L) (Benzodiazepine): CNS depression and paradoxical hyperexcitability in the elderly 1 Nifedipine & Terbutaline: Tocolytics used to suppress preterm labor contractions 2 Methylergonovine: Sustained uterine contraction for control of PPH 3 Oxytocin: Induction of labor and control of postpartum hemorrhage (PPH) 4 Insulin: Management of gestational diabetes 5 Magnesium Sulfate: Prevention of seizures in preeclampsia/eclampsia and fetal neuroprotection 6 Labetalol: Gestational hypertension and preeclampsia 7 Biktarvy, Penicillin G, Azithromycin, & Metronidazole: Treatment of gestational infections (HIV, GBS, syphilis, chlamydia, gonorrhea, trichomoniasis) (Tocolytics): Hypotension and tachycardia; pulmonary edema (terbutaline only) (Oxytocics): Uterine hypertonicity, uterine rupture, and maternal water intoxication Uterine hypertonicity, uterine rupture (CNS Depressant): Magnesium toxicity (loss of DTRs, RR <12, CNS depression) Biktarvy (Antiviral): Lactic acidosis and nephrotoxicity (Pancreatic Hormone): Hypoglycemia and hypokalemia (Beta Blocker): Hypotension and bradycardia 1 Garlic: Cardiovascular health (BP/cholesterol) and antimicrobial effects; Ginger: Vertigo, nausea, and anti-inflammatory needs 2 Cranberry: UTI prevention 3 Coenzyme Q-10: Mitochondrial encephalomyopathies, CHF, and statin-induced myopathy 4 Echinacea: May interfere with immunosuppressant drugs 5 Flaxseed: Constipation and dyslipidemia 6 St. John’s Wort: Depression Immunostimulant for flu prevention; contraindicated in pt's taking immunosuppressant drugs can decrease anticoagulant effects of warfarin; decreased BP when combined with antihypertensives, risk of hypoglycemia with insulin May increase INR with warfarin therapy GI adverse effects and decreased absorption of other medications Serotonin syndrome and multiple drug interactions Increased risk of bleeding 1 Absorption Issues: 2 Sodium: 3 magnesium: 4 Potassium: 5 Calcium: 6 Phosphorus: 7 Drug-Drug Interactions of minerals: Used for fluid balance and replacement. Imbalances are a primary concern for central nervous system function and can lead to seizures antacid, laxative, first-line treatment for Torsades(polymorphic VT),decreases uterine contractions and prevents seizures in preeclampsia osteoporosis and PTH deficiencies. Cardioprotection by stabilizing cardiac membranes (especially in hyperK+), reversal agent for mag toxicity Used for replacement and to help prevent calcium-based kidney stones by binding to calcium in the intestines electrical excitability in skeletal and cardiac muscle; imbalances often first appear as T-wave changes on telemetry, used for pts on lasix(furosemide Potassium given with potassium-sparing diuretics (e.g., spironolactone) significantly increases the risk of life-threatening hyperkalemia Calcium and magnesium can interfere with the absorption of iron and certain antibiotics, such as tetracyclines 1 Fresh Frozen Plasma (FFP) 2 Whole Blood 3 Packed Red Blood Cells (PRBCs) 4 Nursing Safety Protocols for Blood Products: pre-administration 5 Nursing Safety Protocols for Blood Products: verification 6 Albumin indications: 7 Nursing Safety Protocols for Blood Products: Administration: 8 Platelets Hypovolemia, hypoalbuminemia, and burns; it provides oncotic pressure to pull fluid into the vasculature informed consent, type and screen (cross-match), except when O-neg is used; use at least a 20-gauge IV (smaller causes hemolysis) Active bleeding, DIC, burns, shock, and emergent reversal of warfarin; it is rich in clotting factors Massive blood loss from trauma or surgery; replaces all components (cells and plasma) simultaneously Thrombocytopenia or active bleeding with a low platelet count prime tubing with only 0.9%NS, stay with pt for first 15 min of infusion, transfusion must be completed within 4hrs of leaving the blood bank Severe anemia or hemoglobinopathies; used specifically to increase oxygen-carrying capacity Requires a two-nurse check at the bedside to verify the patient's identity and match the unit number and blood type to the order
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