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Mecanismos inflamatorios: respuestas y mediadores

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Mecanismos inflamatorios: respuestas y mediadores

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Claves de la inflamación

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Mitzi Duran
Mitzi Duran
Mexico

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Mecanismos inflamatorios: respuestas y mediadores
 

Mecanismos inflamatorios: respuestas y mediadoresOnline version

Claves de la inflamación

by Mitzi Duran
1

La inflamación tiene un papel protector al eliminar patógenos y reparar tejidos.

2

Los mediadores solubles de inflamación no incluyen citoquinas ni histaminas, solo sustancias lipídicas.

3

Las moléculas de adhesión inhiben la adherencia de neutrófilos al endotelio, impidiendo su migración.

4

La cinética de la respuesta inflamatoria implica una fase temprana rápida y una segunda fase más sostenida.

5

Los mediadores solubles de inflamación incluyen histamina, prostaglandinas y citocinas como IL-1 y TNF-α.

6

Los neutróilos son los responsables de la producción de anticuerpos, función propia de los linfocitos B.

7

La respuesta inflamatoria es exclusivamente perjudicial para los tejidos y nunca beneficia al huésped.

8

El endotelio se desactiva permanentemente durante la inflamación, reduciendo la permeabilidad.

9

La activación endotelial facilita la extravasación de neutrófilos durante la inflamación.

10

Las moléculas de adhesión como selectinas e integrinas permiten la margination y diapedesis de neutrófilos.

 
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