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Pharmacodynamics

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Pharmacodynamics

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About this activity

NURS811 Class 1

Created by

Brooke
Brooke
United States

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Pharmacodynamics
 

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PharmacodynamicsOnline version

NURS811 Class 1

by Brooke
1

Pharmacokinetics - what the does to the

2

Pharmacokinetics explains the relationship better the dose you administer and concentration over tim e

3

The 4 things that are affected with pharmacokinetics : , , ,

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Pharmacodynamics - what the does to the

5

Pharmacodynamics explains the relationship between and

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is the dose required to achieve a given clinical effec t

7

Potency curve shifted to the left - affinity for receptor - potency - dose required
* shift to the right is the opposit e

8

On the efficacy curve graph - a higher plateau is a efficacy and a lower plateau is a efficac y

9

A binds to a receptor and turns on a specific cellular respons e

10

A full agonist instructs the receptor to produce its respons e

11

Examples of a full agonist : ( at beta receptor ) , dopamine ,

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A partial agonist binds to a receptor but can only turn on a cellular respons e

13

A partial agonist is called a - agonis t

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An sits in the receptor and prevents an agonist from binding to i t

15

There efficacy with an antagonis t

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Continuous administration of an antagonist can regulate target receptor s

17

Competitive antagonism is

18

Noncompetitive antagonists bind to a recepto r

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The duration of a noncompetitive antagonist is , this is because new receptors have to be mad e

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agonist binds to the receptor and cause the opposite effec t

21

Effect of two drugs at the same time is called

22

Two drugs added together is greater than their sum with ( 1 + 1 = 3 )

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One drug is enhanced by a drug that has no effect solo - ( 1 + 0 = 3 )

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Giving one drug cancels the other out with ( 1 + 1 = 0 )

25

Therapeutic Index = /

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therapeutic index = margin of safet y

27

Two molecules that are the mirror image of each other are known ans

 
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