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Froggy Jumps
Froggy Jumps

B-oxidacion

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B-oxidacion

Froggy Jumps

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Expo equipo 1

Created by

Liz Cruz
Liz Cruz
Mexico

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B-oxidacion
 

Froggy Jumps

B-oxidacionOnline version

Expo equipo 1

by Liz Cruz
1

La \beta-oxidación del palmitato (un ácido graso de 16 carbonos) requiere de 7 ciclos y genera un total de 8 moléculas de acetil-CoA

2

En el primer paso de la \beta-oxidación, la deshidrogenación del acil graso-CoA da lugar a un intermediario con un doble enlace de configuración cis

3

El aceptor de electrones en el tercer paso de la \beta-oxidación, catalizado por la \beta-hidroxiacil-CoA deshidrogenasa, es el FAD.

4

La tiolasa (acil-CoA acetiltransferasa) utiliza una molécula de agua (H_2O) en el cuarto paso para romper el enlace entre los carbonos \alpha y \beta

5

Durante la hibernación, los osos obtienen casi toda su energía y calor para mantener las funciones vitales mediante la \beta-oxidación de los ácidos grasos.

6

Los ácidos grasos insaturados naturales, al tener enlaces en configuración cis, pueden actuar directamente como sustratos de la enoil-CoA hidratasa sin necesidad de enzimas auxiliares.

7

La oxidación completa de los ácidos grasos de cadena larga e impar produce finalmente acetil-CoA y propionil-CoA

8

La carboxilación del propionil-CoA para dar metilmalonil-CoA es catalizada por una enzima que contiene biotina como cofactor y requiere la hidrólisis de ATP.

9

A diferencia de las mitocondrias, en los peroxisomas la \beta-oxidación no genera ATP directamente, sino que acorta las cadenas largas y produce H2O2

10

En las hojas de las plantas, la función principal de la \beta-oxidación en los peroxisomas es producir grandes cantidades de energía (ATP) para la respiración celular

 
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