Matching Pairs HISTOLOGY: Bones, cartilage, joints, lesson 3Online version MIDTERM by Danillee Faye Mabayag 1 Woven bone (SYNONYMS) 2 Lamellar bone (Location) 3 Lamellar bone (Characteristics) 4 Woven bone (Characteristics) 5 Woven bone (Major location) 6 Lamellar bone (Synonyms) 7 LAMELLAR vs WOVEN BONE Irregular and random collagen. Lightly calcified Developing and growing bones; hard callus of bone fractures Mature bone; 2ndary bone Parallel organized collagen in thin layers (lamellae); regularly spaced cells; heavily calcified LAMELLAR vs WOVEN BONE Immature, Primary, Bundle bone, newly calcified All normal regions in adult bone 1 Compact bone (Location) 2 Compact VS Cancellous bone 3 Cancellous bone (Synonyms) 4 Cancellous bone (Characteristics) 5 Compact bone (synonyms) 6 Cancellous bone (Location) 7 Compact bone (Characteristics) Compact VS Cancellous bone Inner region of bones, adjacent to marrow cavities Interconnected thin spicules/ trabeculae covered by endosteum Parallel lamellae or DENSEpacked osteons, w. interstitial lamellae 80% of all lamellar bone, Cortical bone Thick, outer region (beneath periosteum) of bones 20% of all lamellar bone; Spongy bone; TRABECULAE; bone; Medullary bone 1 Fibrocartilage 2 Hyaline cartilage (perichondrium) 3 Fibrocartilage (Type 1 predominant) (Organ) 4 Hyaline cartilage (Type 2)(Organ) 5 Elastic cartilage (Type 2) (Organ) 6 Elastic cartilage Has perichondrium (except epiphyses and articular cartilage) BRONCHI; TRACHEA; Articular ends and EPIPHYSEAL PLATE of long bones; Fetal skeleton; ARTICULAR and COSTAL cartilage; NO PERICHONDRIUM External EAR; External acoustic meatus, auditory tube'; EPIGLOTTISand other laryngeal cartilage, AURICLE, EUSTACHIAN TUBE Has perichondrium Intervertebral disc; Pubic symphysis; meniscus; insertion of tendon 1 Fibrocartilage (Type 1) 2 Elastic cartilage (Type 2) 3 Hyaline cartilage (Type 2) Type 1 predominantly but has small type 2, cushion, tensile strength and resistance to tear Glassy, smooth, homogenous, structural support, low friction surface in joints; respiratory tract, aggrecan Flexible , dark elastic fibers, aggrecan 1 Vesicular zone 2 Basal zone 3 4 REGIONS in ELECTRON MICROSCOPY 4 Ruffled border 5 Clear zone Active bone RESORPTION (irregular finger like cytoplasmic extend to Howship) Exocytotic vesicles (transfer lysosomal enzymes) ; Endocytotic vesicles (transfer degraded bone); Enzyme product transport Attachment/sealing ; MICROFILAMENTS opposite of ruffled border; MOST CELL ORGANELLES 4 REGIONS in ELECTRON MICROSCOPY 1 2NDARY CENTER OF OSSIFICATION 2 Hypertrophic zone 3 Ossification zone 4 Calcified zone 5 Proliferative zone 6 Resting zone Bone tissue first appears (osteoblast lay bone) 2NDARY CENTER OF OSSIFICATION loss of chondrocytes + calcification Chondrocytes DIVIDE into columns swollen, enlarged degenerative chondrocytes Hyaline cartilage 1 Osteoblast 2 Osteocyte 3 Osteoprogenitor 4 Osteoclast builds bone; Cuboidal, basophilic, osteoid nearby; like PLASMA CELL; ECCENTRIC NUCLEUS Maintains bone; In lacunae, processes in canaliculi' Regular spaced matrix; flat-almond shape, less RER Resorbs bone; Large, MULTINUCLEATED, howship lacunae; DESTRUCTION Stem/precursor cell; Gives rise to osteoblast 1 Secondary center 2 Osteocalcin 3 Type 2 collagen 4 Type 1 collagen 5 Periosteum 6 Primary center 7 Osteon 8 Endochondral 9 Volkmann canals 10 Intramembranous 11 M-CSF and RANKL Flat skull bones Epiphysis 2 polypeptides produced by osteoblast Perforating canals Most long bones; primary center in diaphysis, secondary center in epiphysis Noncollagen secreted by osteoblast rich in ALP; serve as foci for HYDROXYAPATITE CRYSTAL Nourish osseous tissue (oppositional bone growth + trabeculae) Diaphysis Complex; haversian system Bone + fibrocartilage Hyaline + elastic cartilage 1 Howship lacunae or Resorption cavity 2 Articular cartilage 3 Calcium hydroxyapatite 4 Concentric lamellae 5 Type 1 collagen, proteoglycan aggregates; bone-specific multiadhesive glycoproteins 6 Osteon (Haversian system) 7 Regulates hyaline cartilage 8 Cement line supporting structure; an osteon (haversian system) Growth hormone and somatotropin (indirect, insuline like) and somatomedins (direct proliferation) Most abundant in bone matrix areas of bone undergoing resorption, osteoclast lie in depression or cavities Organic matter composed of complex of concentric lamellae; bifurcated cylinder Outer boundary of each osteon Movable joints; lacks perichondrium; diffusion of O2 and nutrients 1 Diarthroses 2 Syndesmose 3 Synostoses 4 Synarthroses 5 Symphyses Free bone movement; Synovial fluid is made up of HYALURONAN United only by bone tx and no movement; SUTURES, thin layers of CT w/ osteogenic cells Join bones by dense CT only; INTEROSSEOUS LIGAMENT of inferior tibiofibular joint and posterior SARCROILIAC joints Immobile joints w/ pad of fibrocartilage between articular cartilage; ALL SYMPHYSES, PUBIC SYMPHYSIS, usually in midline Very limited or no movement
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