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Mass Spectrometry Essentials: Fragmentation and Ions

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MS basics and fragments

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Mass Spectrometry Essentials: Fragmentation and Ions
 

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Mass Spectrometry Essentials: Fragmentation and IonsOnline version

MS basics and fragments

by Mai Elshoukrofy
1

Mass spectrometry identifies molecules by ionizing them to form reactive species that then fragment in characteristic ways . The Molecular Ion ( + . ) or parent ion represents the mass of the original molecule , while the is the most abundant fragment . Fragmentation occurs as radical cations form , with patterns that differ for alkanes , alkenes , alcohols , aldehydes and ketones , and alkyl halides . Notable fragments include M + . + 1 and isotopic peaks , , and specific rearrangements used to diagnose structures .

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