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Glikolisis: Jalur Energi Sel

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Glikolisis: Jalur Energi Sel

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Pengenalan singkat jalur glikolisis

Created by

Nazwa Widya Ulfa
Nazwa Widya Ulfa
Indonesia

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Glikolisis: Jalur Energi Sel
 

Glikolisis: Jalur Energi SelOnline version

Pengenalan singkat jalur glikolisis

by Nazwa Widya Ulfa
1

Slide 1: Apa itu glikolisis

2

Slide 2: Lokasi dan Tujuan

Tesis utama: glikolisis terjadi di sitoplasma. Tujuan utamanya adalah menghasilkan ATP dan reduksi NADH sambil mempersiapkan piruvat untuk respirasi atau fermentasi.

3

Slide 3: Substrat Awal

Glukosa masuk melalui transporters membran. Enzim-enzim mengkatalisis serangkaian langkah yang mengubah glukosa menjadi dua molekul piruvat per molekul glukosa.

4

Slide 4: Langkah Awal Terpenting

Langkah utama memerlukan energi awal: ATP digunakan untuk fosforilasi glukosa, membentuk intermediates yang lebih reaktif untuk tahap berikutnya.

5

Slide 5: Enzim Kunci 1

Enzim hexokinase/glukokinase memfosforilasi glukosa menjadi glukosa-6-fosfat, menjaga glukosa di dalam sel dan memulai jalur glikolisis.

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Slide 6: Langkah 2 hingga 4

Serangkaian reaksi mengubah glukosa-6-fosfat menjadi fruktosa-1,6-bisfosfat, melibatkan isomerisasi, fosforilasi berulang, dan pemecahan menjadi dua molekul triose.

7

Slide 7: Enzim Kunci 2

Enzim Phosphofructokinase-1 (PFK-1) adalah kendali laju utama langkah ini, respons terhadap kebutuhan energi sel dan kadar mitokondria.

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Slide 8: Pembentukan NADH dan ATP

Triose fosfat diubah menjadi piruvat, menghasilkan NADH dan ATP melalui proses substrat-level phosphorylation.

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Slide 9: Hasil Energi

Hasil bersih glikolisis: 2 ATP dan 2 NADH per molekul glukosa, dengan piruvat sebagai produk akhir.

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Slide 10: Regulasi & Variasi

Glikolisis diatur melalui kadar energi, pH, dan kebutuhan anaerob. Dalam kekurangan oksigen, piruvat bisa difermentasi menjadi lactat atau etanol.
 
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