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Glikolisis: Jalur Energi Sel

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Quiz singkat tentang langkah-langkah glikolisis

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Glikolisis: Jalur Energi Sel
 

Glikolisis: Jalur Energi SelOnline version

Quiz singkat tentang langkah-langkah glikolisis

by Nazwa Widya Ulfa
1

Slide 1: Pengantar glikolisis

Glikolisis adalah jalur metabolik yang memecah glukosa menjadi piruvat, sambil menghasilkan ATP dan NADH sebagai sumber energi.
2

Slide 2: Lokasi reaksi

Lokasi: sitoplasma sel, tidak memerlukan mitokondria untuk tahap awal pemecahan glukosa.
3

Slide 3: Tahap investasi energi

Tahap investasi energi: ATP digunakan untuk fosforilasi glukosa menjadi glukosa-6-fosfat, lalu diubah menjadi fruktosa-6-fosfat melalui isomerisasi.
4

Slide 4: Pemiskiran gula karbon

Fruktosa-1,6-bisfosfat membelah menjadi dua molekul gula triose-fosfat: gliseraldehida-3-fosfat (G3P) dan dihidroksiaseton fosfat.
5

Slide 5: Redoks pertama

G3P dioksidasi menghasilkan NADH, kemudian diubah menjadi 1,3-bisfosfoglikerat (BPG). Setiap glukosa menghasilkan 2 NADH.
6

Slide 6: Produksi ATP (substrate-level)

ATP diproduksi melalui fosforilasi tingkat substrat: total 4 ATP terbentuk, tetapi netnya 2 ATP per molekul glukosa.
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Slide 7: Produk akhir tahap glycolysis

Produk akhir: piruvat, NADH, dan ATP. Secara bersih, glukosa menghasilkan 2 piruvat dan 2 ATP serta 2 NADH.
8

Slide 8: Regulasi jalur

Regulasi utama: PFK-1 sebagai langkah pembatas; ATP, AMP, dan sitrat mengatur laju glikolisis; hexokinase dipengaruhi G6P.
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Slide 9: Peran oksigen

Dengan oksigen cukup, piruvat masuk ke mitokondria untuk respirasi. Tanpa oksigen, fermentasi regenerasi NAD+ terjadi.
10

Slide 10: Ringkasan manfaat

Glikolisis menyediakan energi cepat (ATP/NADH) dan piruvat untuk langkah selanjutnya dalam metabolisme sel.
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