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Estatinas y fibratos

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Actividad para farmacología II
Participación para la clase

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Mexico

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Estatinas y fibratos
 

Estatinas y fibratosOnline version

Actividad para farmacología II Participación para la clase

by Alma Camacho
1

Vía del metabolismo de los lípidos que se inicia en el intestino

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2

Los lípidos se transportan en la sangre en forma de. Macromoléculas de lípidos y proteínas conocidas como

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Lipoproteina más grande

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En donde inicia la vía endogena del metabolismo de los lípidos

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Son los responsables de la acumulación, posterior oxidación y formación de la placa de ateroma por los macrofagos

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Forman parte de los efectos pleiotropicos de las estatinas, excepto

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Efecto indeseable más frecuente de las estatinas

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Es la estatina más potente

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La combinación de estatinas con fibratos predispone a miopatias y rabdomiolisis

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Las estatinas se clasifican de acuerdo a la solubilidad y con ellos diminución del porcentaje de LDL

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Son agonistas del receptor PPAR alfa

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Los fibratos predisponen la formación de cálculos biliares

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