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PGx Week 5

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PGx Week 5

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PGx Week 5, CYP3A5

Created by

Yasamin Akhgari
Yasamin Akhgari
United States

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PGx Week 5
 

PGx Week 5Online version

PGx Week 5, CYP3A5

by Yasamin Akhgari
1

what is the primary enzyme responsible for tacrolimus metabolism?

2

Compared to a normal metabolizer of CYP3A5, what is the plasma concentration of tacrolimus for a CYP3A5 poor metabolizer?”

3

Sarah has CYP3A5*1/*6 genotype (intermediate metabolism), what is your recommendation for tacrolimus for her?

4

Patients with CYP3A5 wild-type allele generally require lower doses of tacrolimus.

 
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