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PGx Week 8 Practice Quiz: CYP2D6

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CYP2D6 Part 2: Tricyclic Antidepressants and Phenoconversion

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PGx Week 8 Practice Quiz: CYP2D6
 

PGx Week 8 Practice Quiz: CYP2D6Online version

CYP2D6 Part 2: Tricyclic Antidepressants and Phenoconversion

by Sophia
1

Which of the following TCAs are affected by both CYP2D6 AND CYP2C19 polymorphisms? Select all that apply.

Choose one or more answers

2

According to CPIC guidelines, for which CYP2D6 metabolism status is an alternative to ondansetron recommended?

3

Which of the following medications are affected by CYP2D6 polymorphism? Select all that apply.

Choose one or more answers

4

Patient FS is a CYP2D6 normal metabolizer. However, they are currently taking bupropion, a strong CYP2D6 inhibitor. Which of the following best describes the patient’s likely CYP2D6 metabolic phenotype while on bupropion?

5

For patient FS who is a genotyped CYP2D6 normal metabolizer, but taking bupropion (strong CYP2D6 inhibitor), which of the following medications should be avoided?

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