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farmacologia oncologica

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farmacologia oncologica

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test de farmacologia

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Antonia Lara
Antonia Lara
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farmacologia oncologica
 

farmacologia oncologicaOnline version

test de farmacologia

by Antonia Lara
1

Un fármaco antineoplásico produce puentes cruzados en el ADN principalmente a nivel del N7 de la guanina, bloqueando replicación y transcripción, pero carece de selectividad celular. ¿A qué grupo pertenece?

2

¿Cuál de los siguientes fármacos actúa como antibiótico alquilante tras activación enzimática, generando radicales libres y enlaces cruzados en el ADN?

3

El mecanismo de acción que incluye inhibición de dihidrofolato reductasa (DHFR) y bloqueo de la síntesis de tetrahidrofolato corresponde a:

4

¿Cuál de los siguientes antineoplásicos inhibe la topoisomerasa I, generando roturas de cadena simple del ADN?

5

La estabilización de los microtúbulos e impedimento de su desensamblaje, con bloqueo de la mitosis, es característica de:

6

¿Cuál es el mecanismo principal de la bleomicina?

7

Un fármaco que se intercala en el ADN, inhibe topoisomerasa II y genera radicales libres, corresponde a:

8

¿Cuál de los siguientes grupos se une a la tubulina e impide su polimerización, bloqueando la metafase?

9

Un fármaco que inhibe la timidilato sintasa e interfiere con la replicación del ADN pertenece al grupo de:

10

El anticuerpo monoclonal bevacizumab ejerce su efecto terapéutico principalmente mediante:

11

¿Cuál de los siguientes pares fármaco–blanco molecular es correcto según el contenido?

12

Las neoplasias dependientes de estímulos hormonales mencionadas corresponden principalmente a cáncer de:

 
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