Quiz: TB QUIZ


TB QUIZOnline version 10 QUESTIONS WITH ONE CORRECT ANSWER by Anupama K 1 Name of intern Written answer 2 A 35-year-old HIV patient presents with fever and weight loss. Sputum smear is negative. Best next diagnostic step? Choose one or more answers a Mantoux test b Chest X-ray only c CBNAAT on sputum d ESR 3 Which mutation is most commonly associated with rifampicin resistance? a katG gene b rpoB gene c inhA gene d gyrA gene 4 A patient on ATT develops visual blurring and red-green color blindness. Mechanism? a Retinal toxicity due to isoniazid b Optic neuritis due to ethambutol c Hepatic toxicity d Peripheral neuropathy 5 A diabetic patient with pulmonary TB shows delayed sputum conversion. Most likely reason? a Drug resistance b Poor drug penetration c Immunosuppression d All of the above 6 Paradoxical worsening during ATT in HIV patients is due to: a Drug resistance b Treatment failure c Immune reconstitution inflammatory syndrome (IRIS) d Poor compliance 7 A patient with TB meningitis—drug of choice with best CSF penetration? a Ethambutol b Rifampicin c soniazid d Streptomycin 8 Line probe assay detects resistance to: a First-line drugs only b Second-line drugs only c Both first and second-line drugs d No resistance 9 Which cytokine plays a key role in TB granuloma formation? a IL-4 b IL-10 c TNF-alpha d IL-5 10 A patient on ATT shows non-adherence. Best strategy under NTEP a Stop treatment b Hospitalize c Digital adherence technologies (99DOTS) d Ignore 11 A healthcare worker with latent TB (IGRA positive, no symptoms). Management? a Full ATT b No treatment c Preventive therapy (INH/rifapentine) d Surgery

1

Name of intern

Written answer

2

A 35-year-old HIV patient presents with fever and weight loss. Sputum smear is negative. Best next diagnostic step?

Choose one or more answers

a

Mantoux test

b

Chest X-ray only

c

CBNAAT on sputum

d

ESR

3

Which mutation is most commonly associated with rifampicin resistance?

a

katG gene

b

rpoB gene

c

inhA gene

d

gyrA gene

4

A patient on ATT develops visual blurring and red-green color blindness. Mechanism?

a

Retinal toxicity due to isoniazid

b

Optic neuritis due to ethambutol

c

Hepatic toxicity

d

Peripheral neuropathy

5

A diabetic patient with pulmonary TB shows delayed sputum conversion. Most likely reason?

a

Drug resistance

b

Poor drug penetration

c

Immunosuppression

d

All of the above

6

Paradoxical worsening during ATT in HIV patients is due to:

a

Drug resistance

b

Treatment failure

c

Immune reconstitution inflammatory syndrome (IRIS)

d

Poor compliance

7

A patient with TB meningitis—drug of choice with best CSF penetration?

a

Ethambutol

b

Rifampicin

c

soniazid

d

Streptomycin

8

Line probe assay detects resistance to:

a

First-line drugs only

b

Second-line drugs only

c

Both first and second-line drugs

d

No resistance

9

Which cytokine plays a key role in TB granuloma formation?

a

IL-4

b

IL-10

c

TNF-alpha

d

IL-5

10

A patient on ATT shows non-adherence. Best strategy under NTEP

a

Stop treatment

b

Hospitalize

c

Digital adherence technologies (99DOTS)

d

Ignore

11

A healthcare worker with latent TB (IGRA positive, no symptoms). Management?

a

Full ATT

b

No treatment

c

Preventive therapy (INH/rifapentine)

d

Surgery

You can integrate the game into an LMS compatible with LTI 1.1 or LTI 1.3 such as Canvas, Moodle, or Blackboard. This way, the scores will be automatically saved into the platform’s gradebook.

TB QUIZ

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TB QUIZOnline version

by Anupama K

Name of intern

Written answer

A 35-year-old HIV patient presents with fever and weight loss. Sputum smear is negative. Best next diagnostic step?

Choose one or more answers

Which mutation is most commonly associated with rifampicin resistance?

A patient on ATT develops visual blurring and red-green color blindness. Mechanism?

A diabetic patient with pulmonary TB shows delayed sputum conversion. Most likely reason?

Paradoxical worsening during ATT in HIV patients is due to:

A patient with TB meningitis—drug of choice with best CSF penetration?

Line probe assay detects resistance to:

Which cytokine plays a key role in TB granuloma formation?

A patient on ATT shows non-adherence. Best strategy under NTEP

A healthcare worker with latent TB (IGRA positive, no symptoms). Management?

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