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Ciclo de la Urea – Grupo 5

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Ciclo de la Urea – Grupo 5

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Cuestionario sobre la urea

Created by

Paola Herrera
Paola Herrera
Ecuador

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Ciclo de la Urea – Grupo 5
 

Ciclo de la Urea – Grupo 5Online version

Cuestionario sobre la urea

by Paola Herrera
1

1. Un aumento en la amoníaco en sangre activa indirectamente la CPS1 mediante?

2

2. ¿Qué ocurre en la fase mitocondrial del ciclo de la urea?

3

3. Si se inhibe la enzima ornitina transcarbamilasa, se esperaría una acumulación de:

4

4. El fumarato producido en el ciclo de la urea tiene relevancia metabólica porque:

5

5. El costo energético del ciclo de la urea se considera alto porque:

6

6. La citrulina formada en la mitocondria debe transportarse al citosol para:

7

7. ¿Cuál de las siguientes afirmaciones describe mejor la función de la arginasa?

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8. El aspartato en el ciclo de la urea es importante porque:

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9. Una deficiencia en la carbamoil-fosfato sintetasa I provocaría:

10

10. En la primera reacción del ciclo de la urea, la enzima Carbamoil-fosfato sintetasa forma carbamoil-fosfato a partir de:

Explicación

El amoníaco eleva N-acetilglutamato, que activa CPS1 para iniciar el ciclo.

La fase mitocondrial genera carbamoil-fosfato y citrulina que luego salen al citosol.

OTC bloquea la entrada de carbamoil en la citrulina; se acumula carbamoil-fosfato.

Fumarato entra al ciclo de Krebs como intermediario, facilitando energía.

El ciclo consume energía en varias etapas, equivalentes a 4 enlaces de alta energía.

La citrulina debe entrar al citosol para continuar con la síntesis de urea.

La arginasa rompe arginina para liberar urea y regenerar ornitina.

Aspartato aporta un nitrógeno esencial para formar la urea.

CPS1 deficiente impide convertir amoníaco, causando hiperamonemia.

La CPS1 cataliza la formación de carbamoil-fosfato usando amoníaco y bicarbonato.

 
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