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Fondaparinux

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Fondaparinux

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About this activity

Quiz sobre fondaparinux y anticoagulación

Created by

kiker
kiker
Mexico

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Fondaparinux
 

FondaparinuxOnline version

Quiz sobre fondaparinux y anticoagulación

by kiker
1

¿Qué tipo de fármaco es fondaparinux?

2

¿Contra qué proteasa coagulante actúa principalmente fondaparinux?

3

¿Qué método de reversión tiene fondaparinux?

4

¿Qué indicación principal tiene fondaparinux?

5

¿Cómo se administra fondaparinux?

6

¿Qué característica de ADME distingue al fondaparinux?

7

¿Qué condición es una contraindicación crítica para fondaparinux?

8

¿Fondaparinux tiene actividad anti-Xa o anti-IIa?

9

¿Es seguro usar fondaparinux durante el embarazo?

Explicación

Es un pentasacárido sintético que actúa mediando antitrombina.

Fondaparinux es específico antifactor Xa al favorecer la inhibición por antitrombina.

No existe antídoto específico para fondaparinux; no se revierte con protamina.

Se usa para tromboprofilaxis y tratamiento inicial de VTE (DVT/EP).

Se administra por inyección SC una vez al día, peso ≤ uso según dosis.

Se elimina principalmente por riñones; ajuste en insuficiencia renal.

Contraindicado en CrCl <30 mL/min por riesgo de acumulación.

Su acción es antifactor Xa; no inhibe trombina directamente.

Fondaparinux no cruza la placenta y puede usarse en embarazo según indicación.

 
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