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Matemáticas en Medicina: Dosificación y Análisis

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Matemáticas en Medicina: Dosificación y Análisis

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Aplicación de números en salud

Created by

Eliane Dalys Mamani Villca
Eliane Dalys Mamani Villca
Bolivia

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Matemáticas en Medicina: Dosificación y Análisis
 

Matemáticas en Medicina: Dosificación y AnálisisOnline version

Aplicación de números en salud

by Eliane Dalys Mamani Villca
1

Una dosis de medicamento debe ajustarse a 0,5 mg/kg de peso. ¿Qué dosis para un paciente de 70 kg?

2

Si el intervalo entre dosis es de 8 horas, ¿cuántas dosis en 48 horas?

3

Para administrar 250 mg cada 12 h, ¿mg al día total?

4

Un fármaco tiene Vd de 0,6 L/kg; ¿qué volumen para 60 kg?

5

Si un análisis de datos revela una tasa de infección de 2,5% en 400 pacientes, ¿cuántos casos se esperan?

6

Un medicamento se administra en mg/kg: 15 mg/kg para 25 kg. ¿Dosis total?

7

Un bronceato de vitamina se recomienda 0,8 mg/kg/día para 12 kg. ¿Dosis diaria?

8

La precisión de una medición se expresa como:

9

Para prevenir un evento adverso, se usan tasas de riesgo y RR. ¿Qué mide el RR?

10

Si el peso cambia, ¿qué fórmula ajusta dosis?

Explicación

La dosis correcta es 0,5 mg/kg × 70 kg = 35 mg. 28 mg usa 0,4 mg/kg; 45 mg equivale a 0,643 mg/kg; 70 mg sería 1 mg/kg.

48 ÷ 8 = 6 dosis. 4 dosis serían cada 12 h; 5 no encaja en el intervalo fijo; 8 implicaría cada 6 h.

Cada 12 h suman 2 dosis/día: 250 mg × 2 = 500 mg/día.

Vd total = 0,6 × 60 = 36 L. 18 L sería 0,3 L/kg; 60 L es 1 L/kg.

0,025 × 400 = 10 casos. 5 sería 1,25%; 20 sería 5%; 25 sería 6,25%.

15 × 25 = 375 mg. 25 kg × 15 = 375; 225 es 9 mg/kg; 400 es 16 mg/kg.

0,8 × 12 = 9,6 mg. 7,2 mg sería 0,6 mg/kg; 12 mg sería 1 mg/kg.

Mediciones en medicina requieren exactitud (acierto) y precisión (consistencia).

RR compara el riesgo entre dos grupos. Riesgo relativo es correcto.

La dosis debe ser proporcional al peso para mantener la seguridad.

 
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