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Dapagliflozina: examen corto

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Dapagliflozina: examen corto

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Quiz sobre dapagliflozina

Created by

Departamento de Formacion MLY
Departamento de Formacion MLY
Dominican Republic

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Dapagliflozina: examen corto
 

Dapagliflozina: examen cortoOnline version

Quiz sobre dapagliflozina

by Departamento de Formacion MLY
1

¿Qué grupo de fármacos abarca la dapagliflozina?

2

¿Cuál es la principal indicación de la dapagliflozina?

3

¿La dapagliflozina reduce la glucosa independientemente de la insulina?

4

¿Qué efectos adicionales tiene sobre peso y presión arterial?

5

¿Con qué dosis se inicia y cuál puede aumentarse?

6

¿Qué prueba de seguridad se debe considerar antes de iniciar tratamiento?

7

¿En qué condiciones está indicada la dapagliflozina aparte de la diabetes?

8

¿Puede ser eficaz en pacientes sin diabetes?

9

Qué estudios respaldan la protección cardiovascular en ICC?

Explicación

La dapagliflozina es un inhibidor selectivo de SGLT2, que bloquea la reabsorción de glucosa en el riñón.

Su indicación principal es la diabetes tipo 2; también se usa en IC y ERC.

Su efecto antihiperglucemiante es independiente de la secreción o acción de la insulina.

Conduce a pérdida de peso y leve descenso de la PA.

Dosis inicial de 10 mg/día, aumentando a 25 mg si se requiere.

No se recomienda iniciar si la tasa de filtración glomerular es <30 mL/min/1,73 m².

También se usa en IC crónica y ERC para proteger la función cardíaca y renal.

Es eficaz incluso sin diabetes en casos de compromiso cardíaco o renal.

La protección CV en ICC está respaldada por DAPA-HF y DELIVER.

 
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