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Etanol y Metabolismo Hepático

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Etanol y Metabolismo Hepático

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Efectos del etanol en metabolismo

Created by

DANIELA CAROLINA SANTANA YUMBO
DANIELA CAROLINA SANTANA YUMBO
Ecuador

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Etanol y Metabolismo Hepático
 

Etanol y Metabolismo HepáticoOnline version

Efectos del etanol en metabolismo

by DANIELA CAROLINA SANTANA YUMBO
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1. ¿Dónde se oxida entre el 90 % y el 98 % del etanol ingerido?

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2. ¿Qué enzima cataliza la conversión de etanol a acetaldehído en el citosol?

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3. ¿Dónde se oxida el acetaldehído a acetato?

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4. ¿Qué vía se activa como alternativa con consumo crónico de alcohol, dependiente de CYP2E1?

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5. ¿Qué efecto tiene el aumento de NADH/NAD+ en el metabolismo del etanol?

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6. ¿Qué procesos se inhiben debido al incremento sostenido de NADH?

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7. ¿Qué se genera con el metabolito acetaldehído que es tóxico para el hígado?

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8. ¿Qué consecuencia tiene la deficiencia de ALDH2 en modelos de deficiencia?

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9. ¿Qué etapas describe la progresión del daño hepático inducido por alcohol?

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10. ¿Qué evidencia científica se cita en las conclusiones sobre el metabolismo del alcohol?

 
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