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DNA Replication Trivia

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DNA replication basics

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DNA Replication Trivia
 

DNA Replication TriviaOnline version

DNA replication basics

by Carrie Angel Letac
1

Which enzyme unwinds DNA at the replication fork?

2

Which fragments are synthesized discontinuously on the lagging strand?

3

Which enzyme seals nicks in the sugar-phosphate backbone?

4

Which enzyme lays down RNA primers to start synthesis?

5

In which direction does DNA polymerase synthesize new DNA?

6

What initiates the growth of a replication bubble?

7

Which enzyme relieves supercoiling ahead of the fork?

8

In bacteria, which enzyme removes RNA primers during lagging strand synthesis?

9

What enzyme compacts and rewinds DNA to prevent tangling?

10

What is the semi-conservative outcome of DNA replication?

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Helicase separates the two DNA strands, creating the replication fork.

Okazaki fragments are short DNA pieces synthesized on the lagging strand.

Ligase joins Okazaki fragments and other DNA segments.

Primase synthesizes short RNA primers to start DNA synthesis.

DNA polymerases add nucleotides to the 3' end, moving 5' to 3'.

Replication begins at specific origins in the genome.

Topoisomerase relieves torsional strain from unwinding DNA.

Pol I removes RNA primers and fills with DNA. (In eukaryotes, RNase H also acts.)

Topoisomerase adjusts DNA topology to prevent supercoils.

Each daughter double helix contains one parental strand and one new strand.

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